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Anti-mcm7 Antibody Fab (CAT#: MOM-18435-F(E))

Datasheet
DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human mcm7 Antibody Fab Fragment MOM-18435-F(E) 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Mouse Antibody Fab Fragment is directed against Human MCM7, expressed in Chinese Hamster Ovary cells(CHO)
  • Target
  • MCM7
  • Type
  • Fab
  • Immunogen
  • Recombinant full length Human MCM7 protein
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
  • Specific Activity
  • Tested positive against native antigen.
  • Purity
  • >95.0% as determined by analysis by RP-HPLC.
  • Storage
  • Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.

BACKGROUND

  • Antigen Description
  • Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for "once per cell cycle" DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for S-phase checkpoint activation upon UV-induced damage.
  • Function
  • ATP binding; contributes_to ATP-dependent DNA helicase activity; contributes_to DNA binding; hydrolase activity; nucleotide binding; protein binding; single-stranded DNA binding;
  • Synonyms
  • MCM7; minichromosome maintenance complex component 7; MCM2, MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) , minichromosome maintenance deficient (S. cerevisiae) 7; DNA replication licensing factor MCM7; CDC47; CDC47 homolog; homolog of S. cerevisiae Cdc47; minichromosome maintenance deficient 7; MCM2; P85MCM; P1CDC47; PNAS146; P1.1-MCM3

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